Red and Rover is built on the premise that dogs are cute. They aren't, and therefore the strip doesn't work. I do not understand how this strip appeals to anyone. It's like Family Circus, it's meant to be cute but it's not.
Runners-up: Blondie, Curtis, Family Circus, For Better or For Worse, Frank and Ernest, Garfield, On the Fastrack
If I have kids, I think I'll teach them to curse like this.
Runners-up: Doonesbury, Frazz, Lio, Non Sequiter, Pearls Before Swine, Single and Looking, Speed Bump