Worst:Because nothing is funnier than a recycled joke.
Runners-up: Mother Goose and Grimm (another recycled joke), Rhymes with Orange, Speed Bump (jokes about the latest trend are rarely funny, especially if the trend is five years old)
Typical Lio. Clever idea, nice drawing.
Runners-up: Agnes, Pooch Cafe, Pickles, Sherman's Lagoon, Mutts