Pathetic Meow Sack? Not a very compelling insult.
Runners-up: Baldo, Blondie, Curtis, Family Circus, Hagar the Horrible, Non Sequiter, Pooch Cafe, Speed Bump
Lots of good stuff in this one. Uncool Canadians, Marco Polo, coolishness. Darby Conley just blows away the competition on his good days. Kudos for the threepeat too.
Runners-up: Agnes, Brewster Rockit: Space Guy!, Lio, Pearls Before Swine, Rhymes with Orange, Watch Your Head