Runners-up: Blondie, Close to Home, Frank and Ernest, Hagar the Horrible, Mother Goose and Grimm, Pooch Cafe, Prickly City, Speed Bump
The Garfield strip needs to compensate for poor drawing with an awkward exposition in the first panel. Lio, of course, suffers no such problem. Most comic strip artists could learn from Mark Tatulli's ability to express things without words.
Runners-up: Agnes, Beetle Bailey, Candorville, Frazz, Non Sequiter (I like this strip based on the conflicts inherent in the characters' personalities. When it does not feature that, it often falls flat.), Pearls Before Swine